Single Embryo Transfer

Center for Reproductive Health

Single Embryo Transfer (SET)

Single Embryo Transfer (SET) is a fertility technique in which only one high-quality embryo is selected for transfer into the uterus during an IVF cycle. SET is designed to reduce the risks associated with multiple pregnancies, such as preterm birth and complications for both the mother and babies. This approach maximizes the chances of having one healthy baby while maintaining high pregnancy success rates.

Why Choose Single Embryo Transfer?

SET offers several important benefits, including:

Lower Risk of Complications: Multiple pregnancies (e.g., twins or triplets) come with increased risks, such as preterm labor, low birth weight, and higher rates of neonatal intensive care unit (NICU) stays. SET significantly reduces these risks by aiming for a singleton pregnancy.
High Success Rates: With advancements like Preimplantation Genetic Testing for Aneuploidy (PGT-A), fertility specialists can ensure the best embryo is selected for transfer. This improves the likelihood of implantation and a successful, healthy pregnancy while minimizing the need for multiple transfers
Healthier Pregnancy Outcomes: SET often results in healthier pregnancies with fewer complications compared to transferring multiple embryos. This is particularly important for women who want to reduce the chances of having a high-risk pregnancy

How Does Single Embryo Transfer Work?

During an IVF cycle, several embryos are created. With SET, only one genetically healthy and viable embryo is chosen for transfer. Advances in embryo screening and freezing technology have made this process highly effective. SET can be used with both fresh and frozen embryo transfers (FET), giving patients the flexibility to choose the best time for transfer.

Is SET Right for You?

SET is recommended for women with a good prognosis for IVF, such as those under 35 or those using genetically tested embryos. It can also be ideal for those who want to avoid the risks of multiple pregnancies. Your fertility specialist will help you determine if SET is the best option based on your health, embryo quality, and personal preferences

Center for Reproductive Health

Frequently Asked Questions About Single Embryo Transfer

1. Why not transfer more than one embryo?

Transferring multiple embryos increases the risk of twins or triplets, which can lead to health complications for both the mother and babies. SET reduces these risks while still providing a high chance of success.

2. Does SET lower my chances of getting pregnant?

No, with modern embryo screening techniques like PGT-A, SET has high success rates similar to transferring multiple embryos. This method improves the chances of having one healthy baby without the risks of multiple pregnancies.

3. Is SET recommended for everyone?

SET is generally recommended for women with high-quality embryos, particularly younger women or those using genetically tested embryos. Your fertility specialist will guide you based on your unique situation

4. How is PGT performed?

PGT is performed as part of an IVF cycle. A small sample of cells is biopsied from embryos at the blastocyst stage (day 5-7 of development). The embryos are then frozen while awaiting test results. Healthy, genetically normal embryos are selected for transfer in a future cycle

5. How long do PGT results take?

PGT results typically take about 1-2 weeks to return. During this time, the embryos are cryopreserved to maintain their viability for future transfer

6. Does PGT increase the success rate of IVF?

Yes, by selecting embryos that are chromosomally normal, PGT can increase the chances of successful implantation, reduce miscarriage rates, and improve overall IVF success rates

7. Is PGT safe for the embryo?

PGT is generally considered safe. The biopsy removes only a few cells from the embryo, and modern techniques ensure minimal risk to its development. However, as with any procedure, there is a small risk associated with embryo manipulation

8. Is PGT covered by insurance?

Insurance coverage for PGT varies. Some insurance plans cover it if there is a medical need, such as a known genetic disorder. It is important to consult your insurance provider or a financial counselor at your fertility clinic

If you're interested in learning more about Single Embryo Transfer (SET) or exploring it as part of your fertility treatment, contact the Center for Reproductive Health in Spokane. Our team will provide expert guidance to help you make the best decision for your family-building journey. Reach out today to schedule a consultation and discuss your options with our experienced specialists.